![]() ![]() In nearly all neuroimaging reports, the studied cortical areas are specified further with a Brodmann Area (BA) number. Published online: 23 September 2005 ! Springer-Verlag 2005Ībstract In human brain imaging studies, it is common practice to use the Talairach stereotaxic reference system for signifying the convergence of brain function and structure. ![]() ZillesĬonsequences of large interindividual variability for human brain atlases: converging macroscopical imaging and microscopical neuroanatomy The relative area distortion between the hemispherical maps and the original cortical surfaces for fifteen human brains is analyzed.Anat Embryol (2005) 210: 423–431 DOI 10.1007/s0042-4 ![]() We determined the best size of the spherical cap by minimizing the relative area distortion between hemispherical maps and original cortical surfaces. A Mobius transformation, which is conformal, is used to transform the points on the complex plane so that a projective transformation maps each brain hemisphere onto a spherical segment comprising a sphere with a cap removed. Together, the two hemispheres are mapped to the complex plane using a conformal mapping technique. Defining a cut around the corpus collosum identifies the left and right hemispheres. Starting with a three-dimensional magnetic resonance image of the brain, the cortex is segmented and represented as a triangle mesh. We describe a new approach that maps each hemisphere of the cortex to a portion of a sphere in a standard way, making comparison of anatomy and function across different subjects possible. Methods to unfold and flatten the cortical surface for visualization and measurement have been described in previous literature but comparison across multiple subjects is still difficult because of the lack of a standard mapping technique. Understanding the function of the human brain cortex is a primary goal in human brain mapping. ![]()
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